Metabolic Engineering of Saccharomyces cerevisiae
نویسندگان
چکیده
منابع مشابه
Metabolic engineering of Saccharomyces cerevisiae.
Comprehensive knowledge regarding Saccharomyces cerevisiae has accumulated over time, and today S. cerevisiae serves as a widley used biotechnological production organism as well as a eukaryotic model system. The high transformation efficiency, in addition to the availability of the complete yeast genome sequence, has facilitated genetic manipulation of this microorganism, and new approaches ar...
متن کاملProgress in metabolic engineering of Saccharomyces cerevisiae.
The traditional use of the yeast Saccharomyces cerevisiae in alcoholic fermentation has, over time, resulted in substantial accumulated knowledge concerning genetics, physiology, and biochemistry as well as genetic engineering and fermentation technologies. S. cerevisiae has become a platform organism for developing metabolic engineering strategies, methods, and tools. The current review discus...
متن کاملImpact of systems biology on metabolic engineering of Saccharomyces cerevisiae.
Industrial biotechnology is a rapidly growing field. With the increasing shift towards a bio-based economy, there is rising demand for developing efficient cell factories that can produce fuels, chemicals, pharmaceuticals, materials, nutraceuticals, and even food ingredients. The yeast Saccharomyces cerevisiae is extremely well suited for this objective. As one of the most intensely studied euk...
متن کاملMetabolic engineering of Saccharomyces cerevisiae for lactose/whey fermentation.
Lactose is an interesting carbon source for the production of several bio-products by fermentation, primarily because it is the major component of cheese whey, the main by-product of dairy activities. However, the microorganism more widely used in industrial fermentation processes, the yeast Saccharomyces cerevisiae, does not have a lactose metabolization system. Therefore, several metabolic en...
متن کاملMetabolic engineering of Saccharomyces cerevisiae to improve 1-hexadecanol production.
Fatty alcohols are important components of a vast array of surfactants, lubricants, detergents, pharmaceuticals and cosmetics. We have engineered Saccharomyces cerevisiae to produce 1-hexadecanol by expressing a fatty acyl-CoA reductase (FAR) from barn owl (Tyto alba). In order to improve fatty alcohol production, we have manipulated both the structural genes and the regulatory genes in yeast l...
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ژورنال
عنوان ژورنال: Microbiology and Molecular Biology Reviews
سال: 2000
ISSN: 1092-2172,1098-5557
DOI: 10.1128/mmbr.64.1.34-50.2000